Norvasc Amlodipine tablets What do amlodipine tablets do?AMLODIPINE (Norvasc(R)) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This results in relaxation of blood vessels, which can reduce the amount of work the heart has to do. Amlodipine lowers high blood pressure (hypertension). It also relieves different types of chest pain (angina). It is not a cure.