Lovenox Enoxaparin injection What does enoxaparin injection do?ENOXAPARIN (Lovenox(R)) is commonly used after knee, hip, or abdominal surgeries to prevent blood clotting. Enoxaparin is also used to treat existing blood clots in the lungs or in the veins. Enoxaparin is similar to heparin. Enoxaparin is known as an anticoagulant, and is sometimes called a blood thinner. However, enoxaparin does not actually thin the blood, but decreases the ability of blood to form clots.