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Lamotrigine Lamotrigine tablets or chewable tablets What do lamotrigine tablets or chewable tablets do?LAMOTRIGINE (Lamictal(R)) is effective in helping to control partial seizures (convulsions) in adults with epilepsy. Lamotrigine is also used in adults and children who have generalized (major) seizures (convulsions) due to a special condition named Lennox-Gastaut syndrome. Lamotrigine is usually prescribed with other medications that also help to control the convulsions, although sometimes lamotrigine may be used by itself.