DDAVP Desmopressin tablets What do desmopressin tablets do?DESMOPRESSIN (DDAVP(R)) is a synthetic (laboratory-made) form of the hormone vasopressin (antidiuretic hormone, or ADH) produced by the pituitary gland. Vasopressin helps to keep a regular balance of salts in the blood and to control the amount and frequency of urination. Without vasopressin too much water is lost in the urine. Desmopressin helps to prevent or control frequent urination, excessive thirst, and dehydration associated with diabetes insipidus or with certain brain injuries. Generic desmopressin tablets are not yet available.