Advair Diskus Fluticasone; Salmeterol inhalation powder What does fluticasone; salmeterol inhalation powder do?FLUTICASONE; SALMETEROL inhalation (Advair(TM) Diskus(R)) is for treating respiratory problems due to asthma. Fluticasone; salmeterol is intended for regular use. It will not cure your condition, but can help to reduce asthmatic symptoms. Fluticasone; salmeterol will not relieve an acute asthma attack. Fluticasone; salmeterol can be used along with other inhaled or oral asthma medications.