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Sotalol Sotalol tablets (Betapace(R)) What do sotalol tablets (Betapace(R)) do?SOTALOL (Betapace(R)) belongs to a group of medicines called beta-blockers. Betapace(R) is an antiarrhythmic given to patients with ventricular arrhythmias (rapid, irregular heartbeats) such as ventricular tachycardia. Betapace(R) treats irregular heart rhythm and can slow rapid heartbeats (tachycardia). Betapace(R) can help your heart to return to and maintain a normal rhythm. Generic sotalol tablets are available.